Entries by zu

Extensive intraspecific gene order and gene structural variations between Mo17 and other maize genomes

Nature Genetics        Published:30 July 2018 Abstract:Maize is an important crop with a high level of genome diversity and heterosis. The genome sequence of a typical female line, B73,was previously released. Here, we report a de novo genome assembly of a corresponding male representative line, Mo17. More than 96.4% of the 2,183 Mb assembled genome can be accounted for by […]

N 6 -Methyladenine DNA Modification in the Human Genome

Molecular Cell          Published:19 July 2018 Abstract:DNA N 6 -methyladenine (6mA) modification is the most prevalent DNA modification in prokaryotes, but whether it exists in human cells and whether it plays a role in human diseases remain enigmatic.Here, we showed that 6mA is extensively present in the human genome, and we cataloged 881,240 […]

Adaptation and conservation insights from the koala genome

Nature Genetics    Published: 02 July 2018 Abstract:The koala, the only extant species of the marsupial family Phascolarctidae, is classified as ‘vulnerable’ due to habitat loss and widespread disease. We sequenced the koala genome, producing a complete and contiguous marsupial reference genome, including centromeres. We reveal that the koala’s ability to detoxify eucalypt foliage may be due to expansions within […]

Oak genome reveals facets of long lifespan

Nature Plant       Published: 18 June 2018 Abstract:Oaks are an important part of our natural and cultural heritage. Not only are they ubiquitous in our most common landscapes but they have also supplied human societies with invaluable services, including food and shelter, since prehistoric times. With 450 species spread throughout Asia, Europe and America, oaks constitute a critical global renewable resource. The longevity […]

High-resolution comparative analysis of great ape genomes

Science           08 June 2018 Abstract:Genetic studies of human evolution require high-quality contiguous ape genome assemblies that are not guided by the human reference. We coupled long-read sequence assembly and full-length complementary DNA sequencing with a multiplatform scaffolding approach to produce ab initio chimpanzee and orangutan genome assemblies. By comparing these with two long-read de novo human genome assemblies and a gorilla […]

Genomic variation in 3,010 diverse accessions of Asian cultivated rice

Nature          Published: 25 April 2018 Abstract:Here we analyse genetic variation, population structure and diversity among 3,010 diverse Asian cultivated rice (Oryza sativa L.) genomes from the 3,000 Rice Genomes Project. Our results are consistent with the five major groups previously recognized, but also suggest several unreported subpopulations that correlate with geographic location. We identified 29 million single nucleotide polymorphisms, 2.4 […]

Global profiling of 6mA sites at single-nucleotide resolution in the genome of Arabidopsis thaliana using PacBio sequencing Nextomics program

In April 2018, Nextomics joins hands with research group of Xiaofeng Gu, biotechnology research institute, Chinese academy of agricultural sciences, and research group of Hao Yu, department of biological sciences and Temasek life sciences laboratory, National University of Singapore, to publish a paper titled as “DNA N6-Adenine Methylation in Arabidopsis thaliana” in the journal of Development Cell. […]